Database & Annotations
Apropos is built on top of the Rat, Mouse and Human IPI datasets. IPI provides a comprehensive, non-redundant list of proteins for these three species and also provides extensive database cross references. The comprehensive cross references to the Rat Genome Database, Mouse Genome Database, Uniprot, Entrez Gene and others facilitates the annotation of each record with additional functional annotations.
Orthology Relationships
The sets of IPI records for the three species are tied together into ortholog groups using assignments from the MGD Orthology dataset.
Technical Details
Apropos is written using RubyOnRails and uses a MySQL database. Apache2 and Mongrel are combined to serve static and dynamic content.